African-AmericansVille(the central part at least). Known for it's history of African Americans. Of course other ethnic groups like hispanics and a few whites have been making up residence in this area. Harlem is a very large neighborhood in Manhattan and can be broken up to 3 parts: East Harlem(5th ave and east), Central Harlem(5th ave to St. Nicholas ave), and West Harlem or Hamilton Heights(St. Nicholas and further west) which is basically an extension of Washington Heights as it is predominantly a Dominican area. East Harlem is also predominantly hispanic (mainly Puerto Rican).
Tony: "Are you sure we're in Harlem? I see nothing but hispanics out here."
Hector: "That's because we're in East Harlem."
by neineinein329 July 30, 2012
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The Greatest Collection of Blacks in the Country.
It was further comfirmed today that harlem is 80% Black, while the other 20% are KKK members living underground....
by ItsANotAJoke April 15, 2010
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A ghetto ass neighborhood in Manhattan with sum ghetto (but attractive)hood niggas, project buildings, drug dealers and craxk heads
by BrooklynGirl64 February 21, 2019
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He is very kind, smart, and is good at basketball.
All the ladies fall for him.
Harlem will help a person in need
by Harlem is golden November 19, 2019
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Harlem’s (or the Harlem I know) are dickheads have bad personality’s are dirty mindedcheating arseholes
Harlem’s are dicks
by Fuk Harlem September 01, 2019
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(1)Harlem:

A large town in Manhattan,New York City. It's considered by Harlem rappers(MA$E,Nigga Who ect.) it's the most ghetto-ish place on the East Coast,and mostly a Black community.

(2)Spanish Harlem AKA East Harlem:

The eastern part of Harlem,that consists of mostly Hispanics.
Harlem & Spanish Harlem is da most hoodest place to be noadays.
by GAME50 October 07, 2005
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