Top definition
An expression of severe unhappiness, similar to "Oh man" and "Shit". It can only be said in times of great distress.
-"Bro, your dog just got run over, your car just got wrecked, and your girlfriend just cheated on you with your dad!"
-"Gyuu!!!!"
-"Gyuu!!!!"
by MederiosJohanson October 11, 2010