This is a critical disease in which the patient's arms and/or fingers and/or hands are incapable of daily functions, due to finishing Through the Fire and Flames on expert and/or hard, and/or completing Raining Blood on expert and/or hard.

Briefly, "the realization that each random passerby is living a life as vivid and complex as your own." Originally from the Dictionary of Obscure Sorrows, which has a lot more beautiful neologism definitions like this you might enjoy.