A colorful method of telling someone to either; a) shut the fuck up
b) go the fuck away
c) go annoy the fuck out of someone else
d) an all inclusive phrase of general distaste which includes a-c as well

A command uttered usually after one has said something infuriating or offensive to you.

No honestly go fuck yourself

An incomprehensible amount of anything, used as a measurement rather than a statement.

When someone tells you to go fuck yourself, they are encouraging you to shove your penis up your own asshole by bending it backwards. Or, if you're a female, to grab the nearest phallic object(s) and penetrate your orifices repeatedly. The connotation is that you'll probably enjoy it and will stop annoying everyone.

Basically, means to just for the person to stop everything he/she is doing and find the nearest gun, point it under their chin and pull the trigger. That way they will no longer bother you and you can get some peace and quiet without their pure bullshit spewing from their mouths. If one continues you to harass you after you say this, you legally have the right to make them discover what your fist tastes like. They cannot sue you for any reason.

To tell someone to go away or to just leave you alone or never talk to them ever again.