That greasy fingerprint on the lens of your glasses, left on there by either yourself as a mistake, or some dickish kid who knows how to piss you off. It can't be wiped away, and just spreads if you try to do so. You'll most likely have to deal with it for a while and it gets more irritating the longer it's there.

An exclamation made when your friends or family are teasing you to a point where you can't handle it anymore and a hissy fit is in order.

Derived from a YouTube user's famed outburst following Britney's lackluster performance at the 2007 VMA's.