Effeminate or wimpy guy - usually in jest. Similar to fag or pussy.
Bartender: What'll it be?
Guy 1: A pint o' Smitty's.
Guy 2: A daquiri, please.
Guy 1: Oh man! You big girl's blouse!
by Geedot October 21, 2003
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A male displaying percieved feminine characteristics through actions which cause his peers to think less of him.Being a big girls blouse is much worse than being just a girls blouse, thus it's highly insulting nature.Also used to force a man to do something they fear through peer pressure.
Chad:I don't want to to go sky diving while eating chilli.
Mike:Don't be such a big girls blouse.get in the plane and bring the chilli.
Chad:Fine...
by Seamus83 January 01, 2006
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someone who is grown up but is terrified of certain things, e.g spiders, aeroplanes, the dark
He is some big girls blouse, a spider ran up his leg and he nearly shit on himself.
by Jonno February 19, 2004
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