Abbreviation for "God Damn Son of a Mother Fucking Bitch", the alternative expression to "every road goes somewhere"; to be applied when an individual makes a wrong turn in heavy traffic or misses an exit on the freeway.

GDSOMFB has wider applications than the full phrasing, such as when missing a flight, train, or bus when one is in public and would prefer not to use profanity.

when you're hungover as shit after a spending a night drunk as a skunk