A failure, someone who really messes up.

The safeguarding of Earth and other worlds from biological cross-contamination (i.e. billionaires with too much time on their hands).

Also known as “planetary protection.” Planetary protection / quarantine “reflects both the unknown nature of the space environment and the desire of the scientific community to preserve the pristine nature of celestial bodies until they can be studied in detail.”

There are two types of interplanetary contamination. Forward contamination is the transfer of viable organisms from Earth to another celestial body. Back contamination is the transfer of extraterrestrial organisms, if such exist, back to the Earth's biosphere.

short for "shut the fuck up."

An extreme disappointment, someone who continually makes foolish mistakes and doesn't learn.

A person who is a complete fuckup in life. Someone who can't hold a job, can't get laid, can't mantain a relationship, mooches off everyone like a little parasite and shits on everyone who knows them. Even their own family hates their guts. A complete failure in every aspect of life.

1. To make a mistake; bungle something.
2. To act carelessly, foolishly, or incorrectly.
3. To cause to be intoxicated.

Pretty much an accurate description of the Presidency of George W. Bush.