Fuck You And Who U Run Wit Share definition Flag A expression used as an insult to a person and their friends, family, etc. Andre threatened Christopher's life , so Christoper said boldly "Fuck You And Who U Run Wit!!!" Fuck You And Who U Run Wit by Ace Deuce August 27, 2006 0 0 Get merch Get the Fuck You And Who U Run Wit mug. Buy Now — $32.95 See more merch