When someone is drunk beyond belief. Drunk to the point where homo-sexual behaviour is as standard as breathing. Licking somebody's face is more appropriate than hand shaking.
'He's completely wasted!' 'No.... He's worse. He's duffied'
by panda88888 January 09, 2010
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The blatant act of perving on a girl so much that it looks like you would go so far as to get her up the duff.
It's obvious that Chris really has a thing for Angela. He was duffying her in the gym again.
by RedheadM23 August 05, 2011
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"verb/adjective" A terminology commonly used in the inner city of Baton Rouge, La. It is used as another word to described the act of something being or going "crazy" "gangster" "retarded". It caught on after being profusely used in the local documentary "Thuggin It and Lovin It".
"I done already took over Sherwood... I f***s with them boys in Glen Oaks, they already know I go DUFFY!" --Rambeezy

"Thuggin' It and Lovin' It"
by PrincessDorky August 08, 2009
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Go hard, get retarded, dumb, any dude that steps up gets messed up
by 23565 August 18, 2009
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Duffie is a very loyal girl. If she falls in love with you, she'll never cheat on you. She's usually a bit of a tomboy, but very pretty.
She also has a good sense of humor and can be very sarcastic. Duffie is nearly perfect.
''I made Duffie my girlfriend.''

''Wow, good job! You'll be happy together!''
by grandpajoe November 17, 2013
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