Duffie is a very loyal girl. If she falls in love with you, she'll never cheat on you. She's usually a bit of a tomboy, but very pretty.
She also has a good sense of humor and can be very sarcastic. Duffie is nearly perfect.
''I made Duffie my girlfriend.''

''Wow, good job! You'll be happy together!''
by grandpajoe November 17, 2013
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Duffie is the Squad,Fam,ect but if a nigga try us we gonna beat that ass like a thanksgiving turkey
Duffie squad go hard
by DuffieGirlKay March 02, 2016
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To disrespectfully slide your dirty vagina horizontally up someones face, leaving a slimy residue.
Shut up or I'll duffie your ass
Keep talking shit and I'll give you a duffie
by The Whore and The Virgin April 05, 2009
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The practice of ruining your relationship with a boyfriend/girlfriend and then making your ex feel like shit through tactics such as: Sending them fake self-harming images titles "are you happy now?", fake crying where they can see you, kissing a random person in a night club and then telling your ex straight after.
Duffie-er:
"It's my fault the relationship broke down-- But here! Have all of my problems anyway"

Duffie-ee:
"...wow"
by Yermaw.wan February 09, 2013
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The blatant act of perving on a girl so much that it looks like you would go so far as to get her up the duff.
It's obvious that Chris really has a thing for Angela. He was duffying her in the gym again.
by RedheadM23 August 05, 2011
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