When someone smokes a lot of marijuana in combination with any kind of alcohol and pukes forever at the end of the night.

Drigh-Drunk and high

A pick me is a woman that is willing to do anything for male approval. She will embarrass or throw other women under the bus to achieve this goal. The unfortunate thing about a pick me is usually the men they are trying to seek approval from are of poor quality and treat women badly, leaving little real benefit for the pick me.