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Down Sydrome is simply one of the most hilarious forms of mental defects around. If you can't laugh at Down Sydrome, you can't appreciate it.
That's the stupidest thing I ever heard, bitch must have down syndrome or something.
by Matthew D. Dillon April 18, 2008
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What you call someone who has recently been an idiot, asked an extremely stupidass question or is just a flat-out moron.
Person one: hey look at me i'm licking the floor

Person two: ... do you have fucking down syndrome?

Person one: is the Earth flat?

Person two: you have down syndrome.
by Knee-Grow10 April 17, 2007
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A term for an addiction to the band System of a Down
Mike listens to System of a Down all day, he has down syndrome.
by m-dubya May 28, 2005
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This is a very big problem and is only getting worse as it is spreading very rapidly. The common characteristics of a person carrying the "downer" viruses as its known is impeded movement loud uncontrolled noises that have been reported to sound like zombies. Don't play this sown it is a very big problem as they are now stronger enough in numbers to start being integrated into the general public and are now starting to breed in the open. We must stop this issues as soon as we can before its to late.
look at that kid he has down syndrome.
by SkillfulMmd June 24, 2009
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A mental defect caused at birth, when a human has more than the amount of chromosomes he's supposed to have.

People afflicted by down syndrome have larger or longer fingers and have shorter memory and learning.

The affects cartoons have on humanity include making stupid people look ugly or goofy,
which makes some incompatant bitches make fun of people afflicted by down syndrome because the afflicted people look somewhat "goofy" to them.

People with down syndrome are not autistic btw, because autistic people have brain problems, while people with down syndrome have chromosome problems. See links above.
Dude: "dude2.. my new born cousin was diagnosed with down syndrome..."

Dude2: "Poor him.. I hope he will be able to face those facts in the future."

Dude3: "R0FLZ HES GOT TEH D0WN SYNDR0M!"
*gets PWNZ0RED by a parade of flying blood sucking
breakdancing werewolf bisexual lizard eyed monkeys from mars*

And remember kids! Dont make fun of people with Down Syndrome, OR YOU WILL BE PWNZ0RED BY A PARADE OF FLYING BLOOD SUCKING BREAKDANCING WEREWOLF BISEXUAL LIZARD EYED MONKEYS FROM MARS!!!
-Mii
by FLking August 30, 2007
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Brian: Hey dude do you have your Down Syndrome today?
Kevin: Yea i have my Down Syndrome and i brought golden eye for multi player.
Brian: Sweet.
Kyle: What the hell is a Down Syndrome?
Brian: Jesus Christ Kyle it's a DS.
Kyle: Oh
Audie: Shut up hoe!
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