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When a person is coming down off a drug .
It doesn't have to just be heroin or crack it could also be pills too .
I was so dope sick the first few days I didn't take any drugs.
by sarabby October 07, 2008
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An awesome book written by Walter Dean Myers, really made me think.

by KrustyKrabPizza April 25, 2009
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Adj. When something is considered extremely “dope” or “sick” at the same time. Commonly used to exaggerate how rad something truly is.
Bruh, that chick’s ass is... Dopesick!”

“Bro, That new Vape is... Dopesick!
by WebsterBroseph June 03, 2019
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Something to dope for words, something were there is no word but this to explain.
You kickin' that cat was dopesick!
by Matthew Kutney December 09, 2007
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An undesirable person who is unworthy of their own existence. Their drug of choice is usually heroin, but they will smoke, snort, or shoot any substance. You don't want to touch anything this person has touched previously.
Dopesick will sell us some percocet but we have to give him a ride.
by PerCoceT January 20, 2005
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