1) When someone asks you to not ruin their mood.

2) In simple terms it means to fuck right off.
Umm bitch don’t kill my vibe okay?!
Stop being stuck a buzz kill by killing my vibe!!
by watzgoodmotherfuckers April 16, 2019
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Used by females when having sex/masturbating and they want you to get them hornier
“Don’t kill my vibe daddy
by JustAnotherGuyOnUD September 10, 2020
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