Someone/Something that is incredibly awesome and should not be messed with

Briefly, "the realization that each random passerby is living a life as vivid and complex as your own." Originally from the Dictionary of Obscure Sorrows, which has a lot more beautiful neologism definitions like this you might enjoy.

A word alteration of desolation - means not only despair,despondency and melancholy,but also that such despair has no solution - hence,de-solution.
Hence a desolation that will remain the same.Goddamit.