A grey pegasus pony and minor character in the cartoon series My Little Pony. She is best known for her clumsiness and cross-eyed gaze. Originally named Ditzy Doo, she quickly became a favorite among bronies. She likes muffins and delivering mail.

A stupid, yet hilarious trick on someone

A stupid and hilarious looking face often with an awkward smile or crossed eyes

A Person of Indian Decent that drives a minivan or works at a gas station/711

Awesome youtuber. Famous for doing trolls

Derpies is an increasingly prevalent socially-transmitted disease that impairs mental function in afflicted individuals. Derpies has become as common as one-in-two individuals on average in the world's population. The level of concentration of affected individuals increases the risk of exposure and transmission exponentially. Despite this fact, rural areas appear equally affected as urban areas. Cooperative vigilance and increased awareness are strongly advised as the only effective deterrents to the spread of this illness.

Symptoms of Derpies include:

Decline in common sense
Impairment of motor functions
Reduction in observational skills
Appreciation of reality television
Pattern of poor decisionmaking
Increased laugh response
Reckless driving and parking
Misuse of commonly used words
Distortion of spacial reasoning
Excessive quasi-aggressive
physical contact

If four or more of the listed symptoms apply to you, a friend or a loved one, Derpies may have already taken root in your social environment. Unlike its permanent, sexually-transmitted
cousin; Herpes, the non-permanent Derpies is potentially deadly. It is important for affected individuals to seek academic assistance immediately to mitigate Derpies-associated
risks to your social well-being.

A real word meaning of or related to the word derp.