1."defo" is a slang term used for Deforest which is a small village just north of Madison,Wisconsin. Mainly used by people from Deforest or someone else in the area in reference to Deforest.
2.an area where alcoholics and drug addicts are from

defo = deformed
'Defo' can be used in a variety of ways. It can be used jokingly, in moments of indignation, and even in a casual setting.

A bunch of white kids trying to be ghetto while eating donuts and doing calculus homework outside of Casey's in the either extremely frigid or unbearably muggy air, about 15 miles from Madison, WI.

A certain style of throw during the game of 'Hand Ball' where the player with the ball throws the ball so intensely strong, that it has the capability to knock several of the goalies teeth out.

Defoe Syndrome is a severe physical condition where the body starts to mutate. The legs start to get cellulite all over them. Then the upper lip amazingly gets shorter and shorter until it suddenly dissapears making closing your mouth nearly impossible.

Defoe Syndrome originates in the DeFoe Family starting with Steve and will unfortunately linger on if any female is crazy enough to have Steves Diagnosed DeFoe Syndrome babies.

Definitely for sure!

Used when normally two or more people agree on the same topic, not to be confused with William Dafoe.

food and desert combined with desert as the first meal