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Down syndrome girl. A term coined to describe girls who just look really... off. Oftentimes used to discreetly comment on a girl's facial or fashion appearance, or used literally to comment on a girl's general intelligence.

Variant "DSB" is also used for "down syndrome bro".
"Dude, I'm dating Ashley! She's so hot!"
"Really? She looks like a DSG..."

"I heard she got a 10 on her ACT. Totally DSG."

"How many Downs' do you think that DSG has?"
by snvsk June 18, 2012
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Me: I wish i had my D.S.G
John: Man she's gonna come to u soon.
Me:When
John: God's timing. They always come
by allbright March 15, 2018
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9
Dick Sucking Gums - When someone either intentionally or unintentionally has their teeth removed to provide better and smoother head...

like DSL
My redneck wife has the nicest DSG's ever since the dentist removed whatever teeth were left from all the meth she smoked.

(prison convo) I gonna bust your fuckin teeth out so you have the cutest DSG's whitey!
by Absolute Vengeance March 27, 2007
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A DSG is a DickSuckingGangsta, if you are a DSG you appear to be cool but really are quite gay.
Look at Evan, he's such a DSG.
by pennnykcampbell January 09, 2009
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down syndrom girl. an extremely annoying girl, who asks too many questions. she seems retarded but is actually not.
by Johnny Magnum March 10, 2006
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12
stands for: "down syndrome girl". An ugly girl who looks like she has down syndrome.
dude, did you see that chick?

yeah dude, shes a total DSG!
by Johnny Magnum February 27, 2006
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13
Daily sinner gang. A gang that does vandalism and gets into lots of fights. This gang is very violent. It originated in Indiana and is very feared.
"Crap it's dsg let's walk the other way"
by Wolf master October 22, 2020
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