A thought process held by many film and game producers and makers, in which they want the new product to be like a prexisting product in the thought that it will make the product sell by principle. This rarely works and almost always kills the product from the start. The term comes from the video game "Aliens: Colonial Marines" in which the producers and makers wanted to make a call of duty game with the alien franchise
J: Hey did you hear about the new monster hunter movie?

L: The, WHAT, Oh man i love that game I wonder what its about
J: The description said it was about a military squad that discover a new world that evil monsters are trying to get to the normal world and take over
L: That honestly just sounds like Pacific rim with a monster hunter coat of paint
J: Oh than its a case of Colonial Marine Syndrome CMS
L: Uh, YEAH
by Scrapnell July 11, 2020
Get the Colonial Marine Syndrome [CMS] mug.