Much like the word homesick, its meant to express how much you miss the city you might have visited, or once lived at.
"Ever since I left New York, I've been citysick."

"Being here in this town is making me have a case of citysickness."
by Leah Mac July 17, 2013
Get the mug
Get a Citysick mug for your papa JosΓ©.