Buffsuki is a meme from Doki Doki Literature Club, where the character Natsuki is underfed. Buffsuki is basically Natsuki, just drunk on protein packets.

An angry Natsuki. Just think a mix of Natsuki and John Cena. Even though she might seem small, she is a buff, confident woman that will take you down. Oh yeah, she can also eat 50 cupcakes in a millisecond.

The strongest bitch to live, you don’t stand a chance, nibba.

Best waifu.