A certain male anatomy. It is commonly used by individuals under or usually under the influence of marijuana as a way to express their frustration at simple, everyday tasks. It is common to exaggerate the "O" sound in order to lengthen the saying of the word in order to truly show one's annoyance at life.

from the origin of smooth (ooth) and brain (br). one who is lacking the common brain folds, making them extra stupid. :(

use your imagination; comes in many shapes and forms.

The act of boofing psychedelic drugs and learning all the secret truths of life while simultaneously forgetting how to human properly. May include loss of motor skills and the inability to speak. Ironically, these truths are usually forgotten in full by the end of the trip.