To 'Big-Dick' someone is to show them a lack of respect or ignore their presence. One might get 'Big-Dicked' when attempting to high-five a peer or saying a casual "whattup" and receiving nothing but silent or getting no high-five response, even though the instigator is clearly holding up his or her hand in placement for the interaction. The phrase derives from the theory that male dominance lies in dick size, hence showing a lack of respect to those with a smaller dick. Instead to accusing the aggressor of challenging dick size, the term 'Big-Dicked' was coined to indicate that the challenger thought they had a 'bigger dick'.

One might address the challenger saying, "Hey, are you Big-Dickin' me?" or they might speak about the challenger after the incident stating "Wait a sec, did he just Big-Dick me?"