Top definition
It means Hey You.
It is mainly used when addressing an individual in any given situation to get his or her attention.
Ayo! What time is it?
Ayo, Can I talk to you for a minute?
by E520 October 22, 2003
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Jul 26 Word of the Day
Noun: a friend who is usually only called upon by a friend when a more primary/prominent friend is unavailable.

Taken from the term “second string” in an athletic competition situation. In football, if the star quarterback gets injured during a play, the second string is called off the bench to replace him/her. A “Second String Friend” is essentially benched until needed, if ever.

Synonyms: Plan B, Second Choice, Secondary Friend, Benched Until Needed
I got a call from X the other night. She had an extra ticket to a concert she bought for a friend, but they couldn’t make it so she called me to ask if I wanted to go because I am her Second String Friend.
by Deus-ex-machina August 26, 2020
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2
Just calling somebody out if you don't know their name.
Or expressing how dumb that action was.
Or telling people how cool the action or thing you're seeing is.
Ayo! Bring yo bitch ass here!

Ayo cmon dawg. that shit was dumb as fuck

AYOOOOOOO THAT SHIT WAS LIT ON THE DEAD HOMIES
by wowloserluffy September 24, 2020
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3
a streamlined fusion of the salutation "hey, yo" that goes over extremely well with the modern urban entrepreneur.
"ayo, slim, whatcha'll be on?"
by sinicalypse May 04, 2003
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4
a response for a very suspect or homosexual comment.
Dude 1: That's a big bulge in your pants, what is it?

Dude 2: AYOOOOOOO!!!!!!!!!!!!!
by Sosa Ave July 13, 2008
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6
This is a Nigerian name of the Yoruba dialect which means 'Joy'. It can be combined with other names.
e.g. Ayodele meaning Joy (Ayo) has come/arrived home (Dele)
by nun ur biznaess September 03, 2006
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