The fundemental jazz chord progression. Taken from II-V-I, or more descriptively, IIm7-V7-IM7
An example of a 251 progression in the key of C major is: Dmin7 (2 or II is 2nd scale degree of C) G7 (G is 5 or V scale degree of C) Cmaj7
by kwajazz July 24, 2006
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To be Chill.

Derived from the chord progression used often in jazz to end a phrase or song or to lead into a new segment.
"Hey man, how are ya?"
"Fine, pretty 251"
by Jazzy_Joe May 11, 2009
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If you see someone with the 251 tattoo it will (more often times than not) symbolize the esoteric meaning of the following: 2 boxes of pseudoephedrine + 5 steps worth of instructions = 1 gram of meth. This is the precursor of the shake and bake formula.
Brandon had overheard Bobby talking about how some of his dumb ass friends wanted to get the 251 tattoo while they were in the county jail. Brandon also figured that they would be playing road rash roulette, as soon as the opportunity presented itself.
by yyuryyubicuryy4me June 19, 2018
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