1. Typically a term for professional fighting, but can be used in any fighting situation. Occurs when an individual literally "let's their hands go" and throws punches without thinking about any of them.

2. Going off pure punching instinct.

3. Puttin' a MF'er down.
It was a pretty close fight but you let your hands go and he was done in three seconds.
by RobTheReef November 17, 2009
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telling someone like a bf or gf you cant let them go
Boy: mane w.e im done with you
Girl: omg "i cant let you go" (iclyg)
Boy: well im going
Girl: fuk u lil dick
by an innocent by stander March 23, 2011
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Let one do what one wants to do without any interference or harassment.
Gina: "Where are you going?"
Jimmy: "About to hit the strip club wit my homies. Why?"
Gina: "You always trying to go to the strip club with yo homies! why don't you just stay home?"
Jimmy: "Bitch let my nuts go! Damn!"
by Supa Tite December 17, 2013
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A saying used to illuminate the issue of letting pie go stale. Pie is used as a noun in this form, and refers to a conversation held by close friends. When someone says "Let's not let this pie go stale, they are saying in fact that they do not want this conversation to get boring.
Abby: ....
Bob: .....
Joe: I'm bored of this pie....
Karen:.....
Abby: ...come on people
Abby: Let's not let this pie go stale!
by Kodiak The Bear May 26, 2009
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When you are hotboxing a vechicle and roll down the window to let the smoke go but your friends are paranoid of the cops seeing smoke you would say "fuck the popo let the smoke go" as in saying you don't care the cops will see the marijuana smoke.
Miguel: Elici roll up the window the cops are gonna pull us over and see the weed
Elici: no "fuck the popo let the smoke go"

Quote made by Elici Silva
by Elici Blue April 12, 2017
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The people not letting my submissions go through Fuck off
The people not letting my submissions go through Fuck off
by Tamus something June 14, 2020
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