Misspelling for lol. If you look at the keyboard, you will notice that the letters "ò" and "p" are near "l" and "o".

When it's used by purpose (and it's not a misspelling), I think it should mean "lol".
I use it in the meaning of "Oh, my god...".

(1) Comes from the latin word shite-for brains
(2) First recorded in the early 90's in a small shite village called Kilsby.
(3) Name given to children who by there parents hate.
(4)Used as an abusive slang term in Justifiers.

Acroym for "owned pwned owned". Used only for cases of extreme ownage, uber ownage, or utter ownage.

A word meaning you swear, or you're not lying. If you are to lie to opo, you are banned.

A phrase used between friends to affirm mutual horniness.

Acronym used to refer to others' personal hygiene, particularly in social situations where there may be a large gathering of strangers, such as an anime convention or music festival.

(Widely used and originating from the Yoruba language of Nigeria by popular Musician Naira Marley,) and literally meaning "it's plenty" in English.
O po! is used to show amazement at the size, quantity, grandeur or beauty of something.

It's a very versatile slang that can be used anytime and in many situation.