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Used to address the end of the line in an escalated conversation, debate or exchange. A loss of temper or patience is often the catalyst.

Made famous by actor Christian Bale's infamous outburst on the set of Terminator Salvation.
"I think Sarah Palin got a bad rap in the press."

"Are you kidding?"

"Seriously, she's a terrific role model for women."

"We are done professionally."
by ChanceChance March 02, 2009
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