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Cock-Slapping the Mona Lisa 

This expression is supposed to imply a juxtaposition of a crass or offensive action against something that is held as sacrosanct by someone else.

Coined by Ben "Yahtzee" Croshaw
"For four, what the fuck happened to Clive Winston, you pricks?! In his place we've got some multicoloured, giggly J-pop creature, and you can't play classic rock with that...thing. It's like cock-slapping the Mona Lisa."
-Ben "Yahtzee" Croshaw in his Guitar Hero III review
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The ol' Mona Lisa Twist 

A sex act when a young "artist" tricks an old dirty art teacher into holding up a empty picture frame. He then shoots "patronage" (i.e. semen) all over her face through the frame, and earns his A.
Hey Phillip i heard you got frisky and game Mrs. C the ol' Mona Lisa Twist durring break

Mona Lisa handshake 

A Mona Lisa handshake is when you put your fist in a woman’s asshole and your cock in her vagina, then give yourself a handjob.
Last night I gave myself the best Mona Lisa handshake I had ever had!

The Mona Lisa 

1. When a girl gives a guy a blowjob while simultaneously touching herself until she makes herself cum.

2. Being facefucked by a guy while touching oneself until reaching the point of climax.
He told me to put his dick in my mouth and touch myself because he wanted to feel when I orgasmed through my moaning. He called it the Mona Lisa
The Mona Lisa by Citygworl16 October 10, 2020

sexual Mona Lisa 

Okay the true meaning of the Mona Lisa is when your girlfriend has a heavy flow of her period and you guys have sexual penetration and then you pull your penis out of her bloody vagina and then wipe it on her belly hence the Mona Lisa
She always gets so horny when she's on her period so I had to give her the Sexual Mona Lisa

Mona Lisa 

a girl who is hot from far away, but ugly up close.(just like the painting, looks nice from far away, but cracked and ugly up close)
Lets go talk that girl. O, wait hell no shes a mona lisa.
Mona Lisa by dfs2477 October 1, 2007

Mona Lisa 

A girl sent by a guy to get close to another guy. Her role is to get info on him through (conversation, text messages, etc.) Then she gives that information back to the guy, Then that guy uses the information to set the other guy up. The bitch is basically a informant (🐀). NEVER TRUST A BITCH. 💯
Mona Lisa to me ain't nothin but a bitch.
Mona Lisa by Dead 92315 March 27, 2019