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Dumb Deb Disease

Not a Debbie Downer, just a really dumb Deb. Also not someone named Debbie. Someone so dumb, they don't even know they have the disease. This pandemic has been sweeping across the nation and there is no known cure.
My dumb friend Doris definitely has Dumb Deb Disease.
Do you know Donna? I heard her family just used a whole case of Dumb Deb Disinfectant!
by Dr. Debbie Davidson April 30, 2020
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Diseased Little Munchkin

An obnoxious little person with a shitty personality who is a complete retard. Rejected by all of society and unloved.
Person 1: Why are you so angry?
Person 2: That diseased little munchkin over there told our homeroom teacher that I swore and I got in trouble!
by Brch January 30, 2017
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Mad Cow Disease

1.Used to categorize an affliction that turns a normal woman into a mountainous, sloppy looking woman with a snub button nose and a haircut that was crafted with a lawnmower. Usu. gotten by having low self esteem, recreational drug use, poor diet, and lack of intellectual stimulus.
2.Any other similarly or un-similarly described fatter female afflicted with this ailment.
Ex1: Friend1-" What in the hell happened to her?!"
Friend 2-"You didn't hear? S'shame. She developed Mad Cow Disease..."
Friend-1 "Fuck!"
by TooTrue October 16, 2008
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White People Disease

N, also known as WPD - A fictitious medical condition that pathologizes being White. Symptoms allegedly include having recessive genes, being passive or weak, lacking confidence, being racist, or wanting to discriminate against others. It might also include being nerdy, dorky, having no game, being overly serious, and being unable to sing, dance, play sports or rap properly.
"Don't get me wrong about Tommy. He's a good person, but he has White People Disease. He is always so serious and doesn't like to party like us brothas."
by Purple Gurl February 6, 2015
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Nipple Bone Disease

The worst disease ever been known to mankind. Only the most unfortunate are diagnosed with it.
Oh man did you feel his nipple!

Yeah man, he had it bad....
Yep, a defanite case of nipple bone disease
by george jenkys October 27, 2010
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kirk franklin disease

Being addicted to porn.

Originated when, on an episode of Oprah, Kirk Franklin admitted he used to be addicted to porn.
Damn! I can't stop lookin at this porn! I think I'm breakin out with that Kirk Franklin disease!
by Just The Facts January 8, 2006
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Mad Cow Disease

A legitimate medical term for the symptoms of P.M.S.

A woman with Mad Cow Disease is referred to as a mad cow.
Matt, "Thanks for taking me to the indian casino to play poker tonight. I had to get the fuck away from my wife before she drove me nuts."

Jeff, "You're welcome. I knew you needed it. According to my calender she's got mad cow disease this week."
by dooshkanew August 23, 2009
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