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bless up 

DJ Khaled a spiritual leader uses this term to indicate his thankfulness to god. It can be used as greetings, after hearing good or bad news. The meaning is not quite clear but it's usage is. Bless up.
Random Dude:Yo! Star wars just came out :D
Major DJ Khaled Fan: Bless Up
bless up by Lord Vignesh April 16, 2016

Bless Up 

A term used by celebrity DJ Khaled in order to show reverence to God, or give gratitude to what he has given to you in an opportunity. Also used after hearing something nice, greeting friends, or randomly interjecting statements.
Random Kid: I got an A on the final
DJ Khaled Follower: Bless Up, LIOOON.
Bless Up by Lord Vignesh April 21, 2016

Blessums 

A very patronising way of sympathising with someone. Often said with good intentions, but failing miserably to make the other person feel any better about whatever is troubling them.
<random person> "Shit, I can't feel my arm, fucking rugby!"
<St.Arzy> "Awww blessums."
Blessums by St.Arzy December 16, 2005

bless up 

When you running red lights with the bois like bad asses
Phil ay Alec watch this bless up ... runs red like gets away like a bad ass
bless up by Bad ass boi May 7, 2021

bless up 

Something you immediately say after you mess up.

It was first used in 2001 on BET's Freestyle Friday by rapper Sean Nicolas in his battle against MC Jin (formerly Jin tha MC) after he messed up his lyrics.

Despite the Bless Up, Jin was able to win the battle and secure his place in the Freestyle Friday Hall of Fame.
"Ay yo, I don't mess up, Sean Nicolas Bless Up!

bless up lil nigga 

Step up mothafucka.

A statement said to someone who won't buy your shitty car.
Man 1: I'm not buying that piece of shit car unless I get free hot chips.
Man 2: bless up lil nigga