To protect or overprotect a boy/girlfried in fear that he/she might find interest in someone else. Another way of cuffing is announcing a relationship loudly around a large crowd rather verbally or physically. Think of it as a relationship leash, or handcuffs (thats what it is originated from anyway)
That dude gets any girl he wants in the club. You Better cuff yo girl...
You Dont Let Her Go Nowhere! Are You Gonna Cuff Her Forever?
