1 definition by Miotoxen39
The most amazing girl a guy could ever have. A Karlie is usually smart, funny, and beautiful. If you ever run into one, don't miss your chance! All the guys will rush for a Karlie. But a Karlie ain't no thot, you gotta treat her with respect.
Me: Yo, dude, did you see that new girl, Karlie? She just got here today, and she's smokin'!
Dude: Yeah, she's my girlfriend, man.
Dude: Yeah, she's my girlfriend, man.
by Miotoxen39 December 17, 2014
