1 definition by Big Don Griener

An untreated genital warts/HPV infection that's reached incredible mass in proportion to the rest of the penis. The warts - especially when emerging from beneath the foreskin appear as a "mane" - hence, Lions Mane to describe the condition.
Careful with those 5-dollar hoes, they'll probably give you Lions Mane.
by Big Don Griener April 27, 2006
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