Slang term for the process of making homemade crystal meth. Very popular in rural states such as Tennessee and Kentucky. Ingredients consist of several household chemicals mixed with crushed up cold pills containing ephedrine in a 2 liter soda bottle. See also pillbilly.
Did you here about those stupid pillbillys from Tennessee? They were making some shake and bake in the back seat of their car, and the bottle exploded.
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