Extremely aggrivated, angry, annoyed, and/or dissapointed in any given situation.
It's miffed to the 100th power.
(Often used in conjunction with variations of the word 'fuck')
"That guy just cut me off, and I'm so fucking moffed up right now!"
"I was about to break up with my girl, but she dumped me first. Moffed me the fuck up!!!"
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