A newly-established term stemming from the internet social network crowd, meaning to remove someone from a list of friends. The term is misleading because usually neither of you were friends to begin with. "Defriending" is essentially a way of cutting off already useless communication with cyber-people.
Typical Person: "I had to totally defriend Margaret Mary. I don't want that slut looking at my profile anymore."
Sarcastic Person: "Sounds like the breakup was hard on everyone."
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