Not opposed to, neutral about, or actively-interested in the (usually mutual) use of illicit substances (ranging from "poppers" to marijuana to cocaine and many others) as an accompaniment or adjuvant during sexual activity. Often used in "profiles" posted on gay web-sites or in gay chat-rooms.
"I'm Matt....6'2," 180 lbs, broad shoulders, 8"cut, 30"w, mostly a top, and chem friendly."
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