An adjustment to the expression "You're dead to me," which implies that the target may as well be dead in the speaker's eyes, "You're dude to me" is a statement generally made by men to platonic female friends that the speaker no longer sees as women (and therefore objects of lust). Said mostly in jest or in protest to accusations of hitting on said female friends.
Jamie, I would never grab your ass. You're dude to me.
Oh, that is just disgusting -- look at those hairy pits! You're totally dude to me now!
Girl: Do you think I'm hot?
Guy: You're attractive, but you're dude to me.
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