A vagina. May be used colloquially, as in the Bronx.
The Vagina Monologues, by Eve Ensler, lists "Schmende" as one of many regional terms for the vagina:
"In Westchester they called it a Pooki, in New Jersey, a twat. There’s Powderbox, a Poochi, a Poopi, a Peepe, a Poopelu, a Poonani, a Pal and a Piche, Toadie, Dee dee, Nishi, Dignity, Monkey Box, Coochi Snorcher, Cooter, Labbe, Gladys Seagelman, VA, Wee wee, Horsespot, Nappy Dugout, Mongo, Mooky, a Pajama, Fannyboo, Mushmellow, a Ghoulie, Possible, Tamale, Tottita, Connie, a Mimi in Miami, a Split Knish in Philadelphia, and a Schmende in the Bronx."
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