When someone takes too many pills and enters a state of shock, sometimes resulting in death.
When someone's behavior or actions are just too much for someone else's liking. This is usually excessive or annoying behavior. In cases such as this, the first person is said to be OD.
After hours of circling around looking for women to bring back home...
Arnold: Let's go home, man.
Nico: Maybe around the corner.
Arnold: Come on, man. I'm tired.
Nico: Wait, hold on. There should be chicks two blocks from here.
Arnold: You for real?
Nico: Yea, man. I know they're there.
Arnold: Nico, you're OD man.
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