An unpleasant, cruel, or maliciously insane woman. The female incarnation of Evil Itself.
Often used to refer to female math teachers.
Taken from the the unpleasant character in Shakespeare's Macbeth.
Student: Who do you have for math next semester?
Friend: Mrs. Whitman, you?
Student: Roberts. Wait--Did you say Whitman?
Friend: Yeah, why?
Student: Watch out, man. She's like freaking Lady Macbeth.
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