1. Any woman with a prediliction for doing especially obnoxious or annoying things
2. Any woman who interferes with a man's right to do his man things
3. A temporary condition caused by pissing off someone else
Yo, did you catch the game last night?
No, my girl caught a case of Dumb Bitch Syndrome and made me watch Sex in the City instead!
Cut me off? You must have a serious case of Dumb Bitch Syndrome
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