A point in time when you or your associates recognize the girl you hooked up with is grotesque and/or overweight.
After I remembered that Rosie O'Donnell gave me a handjob last night, I knew it would be a Dennehy moment for the rest of my life.
Bro, Did I just see you with Amy Poehler back at Lindsey Lohan's house? Denehy moment.
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