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zOMG is a varient of the all-too-popular acronym "OMG", meaning "Oh My God".

The "z" was originally a mistake while attempting to hit the shift key with the left hand, and type "OMG"

Also used in all-caps, 'ZOMG' is generally used in a sarcastic manner, more often than not a humiliating fasion. It is also used as a device for stating the obvious.
"zOMG! you r teh winz!!one!!eleven!"
zomg by ectweak August 31, 2005
Zomfgz (zoh my fucking godzorz) is the neo generation zomfg invented by a jamerican cult in Tokyo. The word has managed to expand throughout the world thanks to the zomfgz campaign initiated by Sabian Ramirez.
Zomfgz i fucking ownzed that roflcopter

zomfgz by Sabien May 3, 2007
One of the hardest bloons in bloons TD battles and usually sent by an attack of a high level player
Oh No! How did he send me a ZOMG already!!!
ZOMG by Kalencool514 September 24, 2015
A variation of OMG. The Z doesn't stand for anything; the word was accidentally invented by users intending to hit the Shift Key instead of Z.

It was used by some gamers for a time in 2004. In 2006, its usage became widespread.
ZOMG! That mp3 player is awesome! *orders*
zomg by goodguy5 June 24, 2006
1. One of the games on gaiaonline.
2. When using OMG more onlinely.
1. "Hey, did you play zOMG! yesterday?"
2. zOMG's!, I moose yuuu.
zOMG! by BWAHAHAHA. Yup May 3, 2009
ZOMG was the ruler of the planet XYRZON until 2451 AD, when he was overthrown by KFOP after the battle of SHMUR. the battle marked the violent end to ZOMG'S noble reign as ultra-lord. KFOP soon proved to be an incapable ruler of XYRZON, and the planet collapsed into chaos in 2453. since that day, the residents of XYRZON have used ZOMG as a declaration, nay, an exclaimation of hope. hope that one day peace shall return to XYRZON, on the shoulders of a truly worthy king.
ZOMG, i love cupcakes.
zomg by VISION LOSER January 22, 2007