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1.
a situation concerning zits; the appearance of zits on ones face
You have a serious zituation going on on your ugly face.

Please take care of that zituation. Pronto.
by jkkkkkkk December 21, 2008
 
2.
When one is having an unfortunate situation involving facial acne. This situation can last days, weeks, months or years.
As I was popping one of twenty zits on my face, I turned to my friend, Jacqueline, and said, "I can't go to this party when I'm in the middle of this horrible zituation!"
by SALLY AND JACQUELINE October 29, 2008
 
3.
A commonly encountered predicament, Where when first gazing into the mirror you have a small family of pimples farming the landscape of your face...

Zit Pimple}
Gentleman A: Will you be attending the discotheque tonight?

Gentleman B: Not likely I have a pretty serious zituation on my hands here.
by The seeker!! December 11, 2008
 
4.
a situation concerning zits; the appearance of zits on ones face
You have a serious zituation going on on your ugly face.

Please take care of that zituation. Pronto.
by Jacqueline Kemp October 07, 2008