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1.
an slightly scared exclamation similar to "holy crap" or "yikes". Made famous by Shaggy in Scooby Doo
"Yowsers, iiiiiiiiiis that a ghost in there Scoob?"
by Doctor Livingstone June 02, 2005
 
2.
holy shit
Yowser!! that girls got some tigobitties!!
by the realy cheeky bastard September 23, 2009