Top Definition
Combination of the terms yo, as a greeting, and mofo, in one word. Not necessarily an insult, often used as a greeting to a long term friend similarly to nigga, though it can be a weak insult when applied to a stranger or enemy.
"Yomofo, howz it hangin?"
"Yomofo, get off ma turf!"
by jesus April 09, 2005

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