Abbreviation for You're On Your Own. Something you say after a stupid person says YOLO, letting them know that you have no part in what stupid thing they're about to do.
Guy 1: Hey, I'm gonna go bungee jump off a bridge, YOLO!
Guy 2: Uh, YOYO bro. Go be stupid by yourself.
by ilikechickennn August 22, 2012
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"You're Only Young Once"

YOYO is a motivational phrase that nourishes the pursuit of happiness in young people. Unlike similar abused phrases, such as YOLO, YOYO remains positive and is seldom used by prepubescent girls who seek an excuse to expose their chest or by idiots who need a catchphrase for their Jackass-like stunts.

But there's much more to YOYO...

YOYO is not merely a term. It's a way of thinking. It's a state of mind. The basic principle of YOYO states that the journey, not the destination, is what permeates us with happiness. Thus, the start of the journey, the beginning of our life is of vital importance. The end could be anything. The end could be a slow, painful, lung cancer... or a sudden plane crash. Ergo, the most rational course of action is to give more importance to our youth and not the end.
Adriana tried to butt-rape me with a broom. I said no. She said "Come on! YOYO!"

My friend used to be a meth addict. All he needed to heal was to hear me say, "John, YOYO." - He's been clean for 2 years now.
by pcordon August 17, 2012
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YOYO - "You're own your own." Often used when people ask Mom a particularly stupid question regarding her duties as cook, janitor, maid, chauffeur, legal adviser, boundary maintainer, dispute negotiator, personal no-deposit ATM, etc.
The answer to the question, "What's for dinner?"

YOYO - You're on your own!
by Marthakay March 20, 2007
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You're only young once
Some retard thought it was cool to make his/her own version of YOLO
Kid 1 : Aren't we a bit too young for cigarettes?
Kid 2 : YOYO bro..
by SomeoneToHate June 2, 2012
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You Only Young Once
Stranger: Man don't go on dat rollercoaster ride

Lil boy: I needa go! Im under 12, its half price!

Stranger: Dam, u right #YOYO
by fugicalz April 3, 2012
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a term coined by @509cougar on twitter meaning You're Only Young Once, derived from Drake's YOLO. There are many things you can do in a lifetime, but only some can/should be done during your youth.
Michaela: girl, I'm not partying tonight, I've got too much homework to do.
Tiona: YOYO.

40 year old: Bro, lets go hit up the WSU frats tonight.
25 year old: um, dude, YOYO and ya time is up.
by 509cougar February 10, 2012
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